Methods for generating and colonizing gnotobiotic zebrafish
نویسندگان
چکیده
منابع مشابه
Antigenic variation of Streptococcus mutans colonizing gnotobiotic rats.
Strains of Streptococcus mutans representative of serotypes b and d exhibited antigenic variation in both the oral cavity and in the intestinal canal of gnotobiotic rats. Laboratory-maintained cultures did not vary. The antigenic alterations observed were: (i) loss of detectable levels of both weakly reacting "strain" antigens and the type antigen; (ii) decreased production of the type antigen;...
متن کاملislanding detection methods for microgrids
امروزه استفاده از منابع انرژی پراکنده کاربرد وسیعی یافته است . اگر چه این منابع بسیاری از مشکلات شبکه را حل می کنند اما زیاد شدن آنها مسائل فراوانی برای سیستم قدرت به همراه دارد . استفاده از میکروشبکه راه حلی است که علاوه بر استفاده از مزایای منابع انرژی پراکنده برخی از مشکلات ایجاد شده توسط آنها را نیز منتفی می کند . همچنین میکروشبکه ها کیفیت برق و قابلیت اطمینان تامین انرژی مشترکان را افزایش ...
15 صفحه اولSimple Methods for Generating and Detecting Locus-Specific Mutations Induced with TALENs in the Zebrafish Genome
The zebrafish is a powerful experimental system for uncovering gene function in vertebrate organisms. Nevertheless, studies in the zebrafish have been limited by the approaches available for eliminating gene function. Here we present simple and efficient methods for inducing, detecting, and recovering mutations at virtually any locus in the zebrafish. Briefly, double-strand DNA breaks are induc...
متن کاملGnotobiotic zebrafish reveal evolutionarily conserved responses to the gut microbiota.
Animals have developed the means for supporting complex and dynamic consortia of microorganisms during their life cycle. A transcendent view of vertebrate biology therefore requires an understanding of the contributions of these indigenous microbial communities to host development and adult physiology. These contributions are most obvious in the gut, where studies of gnotobiotic mice have discl...
متن کاملMethods for Generating Explanations
A computer program that models an expert in a given domain is more likely to be accepted by experts in that domain, and by nonexperts seeking its advice, if the system can explain its actions. This chapter discusses the general characteristics of explanation capabilities for rule-based systems: what types of explanations they should be able to give, what types of knowledge they will need in ord...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature Protocols
سال: 2008
ISSN: 1754-2189,1750-2799
DOI: 10.1038/nprot.2008.186